RNA Details
Disease Name
kidney diseases
Tissue
kidney
RNA Symbol
mir-217
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
homo sapiens
Detection Methods
NA
Target
WNT5A
Pathway
WNT SIGNALING PATHWAY
PubMed ID
Title
MiR-217 mediates the protective effects of the dopamine D2 receptor on fibrosis in human renal proximal tubule cells
Year
2015
Function
Carrying D2R snps resulting in D2R downregulation have increased TGF-beta1 that is mediated by decreased regulation of the miR-217-wnt5a-Ror2 pathway.